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New nano/microfluidic platforms for biosensing applications 
Friday, 14 June 2019, 10:00
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New nano/microfluidic platforms for biosensing applications

Prof. Amy Shen , Micro/bio/nanofluidics Unit, Okinawa Institute of Science and Technology, Japan

Micro/nanofluidics has emerged in recent years as a powerful method of manipulating fluids at small length-scales. To highlight their versatility and great potentials, I present 2 simple nano/microfluidic platforms to showcase how nano- and microfabrication techniques can be coupled with fluidics for nanoplasmonic biosensing and immunoassay applications.
(a) Nanoplasmonic platforms for multiple biosensing applications: We develop a nanoplasmonic platform with remarkable biocompatibility, for long-term survival of prokaryotic and eukaryotic cells, thereby enabling nanoplasmonic based cell bioassays. This nanoplasmonic platform is used for monitoring mitosis of fibroblasts for 7 days, E. coli biofilm formation, and DNA polymerase activity in real-time. In addition, the same nanoplasmonic platform is used to conduct routine protein/DNA based immunoassays with a limit of detection of ∼66 zM.
(b) Making Waves in a Total Capture Nanofluidic Immunoassay: understanding nanoconfinement phenomena is necessary to develop nanofluidic technology platforms. We demonstrate a convection limited nanofluidic immunoassay that achieves total capture of a target analyte, and an apparent shift in the reaction equilibrium due to nanoconfinement.

Location ICN2 Seminar Hall, ICN2 Building, UAB
Contact This email address is being protected from spambots. You need JavaScript enabled to view it.
https://icn2.cat/en/events/eventdetail/1071/new-nano-microfluidic-platforms-for-biosensing-applications

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